UTERUS

Technique

Level of
evidence1!

Single centre/
Multicentre/
metaanalysis

Indication

Patient prep

Data acquisition
requirements

Image processing
algorithm

Recommended
biomarkers/
primary end-point

Size/ Morphology

 

 

12-5!

Single centre & Multicentre

Detection, staging, treatment response

IM antiperistaltic agent

Sagittal, axial and coronal oblique
DWI recommended
DCE

Manual documentation by trained observer


Recommended
biomarkers/ secondary
end-point

DCE-MRI

 

15-9!

Single centre

Staging

IM antiperistaltic agent

3D fat-saturated T1W 2min30s after contrast medium administration

Manual documentation by trained observer

DWI (visual)

 

15, 10!

Single centre

Staging

IM antiperistaltic agent

At least 2 b-values (b=0-50 and b=800-1000 s/mm2)

Manual documentation by trained observer

             

Biomarkers in development/
exploratory not
recommended

ADC and ADC histogram

111, 12!
213, 14!
315, 16!

Single centre

Differentiation benign and malignant, staging, histopathological tumour features

IM antiperistaltic agent

At least 2 b-values (b=0-50 and b=800-1000 s/mm2)

Monoexponential data fit, first order histogram parameters

Multiparametric MR

 

317!

Single centre

Staging and histopathological tumour features

IM antiperistaltic agent

At least 2 b-values (b=0-50 and b=800-1000 s/mm2)

Monoexponentional data fit, first order histogram parameters

Radiomics

 

318!

Single centre

Histopathological tumour features

IM anitperistaltic agent

T2W, DWI and dynamic DCEs

No consensus available

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